Hartsville South Carolina Car Rentals

It's easy to find rental car options in Hartsville, SC when you let RoadsideAmerica.com help! You can make an online reservation with a Hartsville, South Carolina rental car agency after you select from a range of rental car companies, vehicle types, and rates. Compare your rental car options in Hartsville, South Carolina by filling in the form below with your desired dates and other information. Pick the vehicle that's right for you, your passengers and your activities, whether it's a road trip or a business mission.

To view cities close to Hartsville, SC also offering car rentals, click here.

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To find Hartsville, SC car rentals, simply enter your itinerary into the search box below.

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Smarter Car Renting

Here are car rental tips from the road trip-seasoned editors of RoadsideAmerica.com:


•  Damaged: Always carefully eyeball your vehicle before leaving the rental agency, whether you're in Hartsville or East Podunkville. The last renter may have pulled in after a meteor shower! Prior scratches, dents, and other vehicle damage can cause extra headaches and costs if not noted before you leave the rental car lot. If you see any damage on the car's exterior and interior before you leave, make sure it's noted on the rental car papers, and point it out to an agency employee. This will resolve any questions that could arise when you return. And avoid meteor showers.

•  Fear of the Unknown: Unfamiliar with the streets of Hartsville? Consider adding a GPS navigation system to your rental. GPS provides turn-by-turn directions to a number of Hartsville attractions and businesses, and is offered by almost all Hartsville car rental agencies. The GPS helps you navigate like some mythical Greek God of Navigation! You can also add your own portable GPS on your handy windshield sucker, but remember to take it all with you when you turn in the car at the end of your trip.

•  Under 25? Everyone over 25 assumes you are an awkward and unpredictable risk behind the wheel. Ridiculous, you say, without taking your eyes off the road. But be sure to check with Hartsville South Carolina car rental companies about their specific policies. Some agencies require the driver to be at least 25 while other rental companies may allow younger drivers to rent for an additional fee. Have more than one driver? Be sure to ask if additional charges apply for more than one person driving the rental car.

Click here to see Hartsville attractions

Hartsville SC Area Attractions

  • Coker College
  • Darlington Raceway (6.56 miles)
  • Florence Darlington Tech College (17.59 miles)
  • Florence Civic Center (18.45 miles)
  • Florence Museum (21.43 miles)
  • Mc Leod Regional Medical Center (21.84 miles)
  • Healthsouth Rehabilitation Hospital (22.03 miles)
  • Carolinas Hospital System (23.71 miles)
  • Francis Marion University (24.76 miles)
  • Morris College (33.41 miles)
  • Tuomey Regional Medical Center (34.30 miles)
  • Sumter County Museum (34.31 miles)
  • University of South Carolina - Sumter (34.47 miles)
  • J W Dillon House Museum (40.02 miles)
  • St Eugene Medical Center (40.86 miles)
  • Scotland Memorial Hospital (43.36 miles)
  • North Carolina Motor Speedway (45.80 miles)
  • University Of South Carolina - Lancaster (47.56 miles)

Hartsville rental guide

The following car rental companies are available in Hartsville South Carolina
Click on the logo to view the locations and average rates.

Enterprise Rent A Car Locations in Hartsville


1109 S. Fifth St
Hartsville SC US 29550-5797

Average Hartsville SC rates for Enterprise


  • Compact:   $45.14
  • Economy:   $45.14
  • Full-Size:   $52.49
  • Luxury:   $83.99
  • Mid-Size:   $47.24
  • MiniVan:   $83.99
  • Premium:   $55.64
  • Standard:   $49.34
  • SUV:   $83.99

If you like the services of a particular car rental company, no problem! We offer a variety of national brand car agencies that operate in Hartsville. Choose to look at only options from a specific rental car brand, or compare rates and vehicles from others by using the search box above. And remember to enter in your discount or reward number during online check-out when you rent your car in Hartsville, SC.