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Santa Fe, New Mexico: Big Molecule of the Cognition Enhancer

In 1999 a drug company built a big molecule of its experimental "Cognition Enhancer." The drug failed to win approval, and now all that's left is the big molecule, surrounded by weeds, vandalized with spray paint.

441 Gregg Ave, Santa Fe, NM
North side of the city. From US Hwy 84/N. St. Francis Drive turn west at the stoplight onto Alamo Drive, then immediately turn right onto Calle Mejia. Drive one block. Turn left onto Gregg Ave. You'll see the sculpture there, on a small hill on the right.
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Visitor Tips and News About Big Molecule of the Cognition Enhancer

Reports and tips from visitors and Roadside America mobile tipsters. Some tips may not be verified. Submit your own tip.

Big Molecule of the Cognition Enhancer.

Big Molecule of the Cognition Enhancer

Larger than expected! No graffiti! Difficult to see from the main road. Be ready to turn on to the small road off of the large road.

[Jan Dunlap, 07/28/2020]

Big Molecule of the Cognition Enhancer.

Big Molecule of the Cognition Enhancer

The Big Molecule of the Cognition Enhancer is currently free of graffiti.

[Conor S., 04/01/2018]


Big Molecule of the Cognition Enhancer

Graffiti is gone! The big molecule looks cared for and loved.

[LamFam, 06/16/2015]


Giant Molecule

Daylight Chemical Information Systems erected a large stick-and-ball molecular model sculpture outside their Santa Fe offices in 1999. The sculpture is a chemically-accurate depiction of a new (in 1999) candidate drug. Black balls represent carbon atoms, yellow are sulphur, red is oxygen, blue is nitrogen. Unfortunately, the drug never made it to the big leagues, but at least it is still very big in Santa Fe. Taggers have added their contributions to chemistry. (Thanks to Pauline Ho for telling me about this).

[Wm Breiland, 04/08/2014]

A plaque at the base of the molecule identifies it as "Cognition Enhancer."

Nearby Offbeat Places

Big Dynamite and Gold Golf BallBig Dynamite and Gold Golf Ball, Santa Fe, NM - < 1 mi.
Big Dog SwingBig Dog Swing, Santa Fe, NM - < 1 mi.
Burro AlleyBurro Alley, Santa Fe, NM - 1 mi.
In the region:
Boondoggle Conquistador Visitor Center, Alcalde, NM - 29 mi.

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